Lytic effect of mycobacillin and its derivatives on erythrocytes.
نویسنده
چکیده
Mycobacillin as well as its O-acetyl (tyrosyl and seryl) and ester derivatives is known to have antifungal activity. The antibiotic also possesses hemolytic activity. This latter property is not appreciably altered by partial or complete esterification of its free carboxyl groups. On the other hand, acetylation of the molecule at the two tyrosyl hydroxyl groups nullifies selectively the hemolytic activity.
منابع مشابه
Some observations on the nature of reactive groups involved in reversal of mycobacillin inhibition by sterols and lipids.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1977